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Vita C Infusion Mikrodermabrazja - Twoje Klucze do Promiennej Skóry
What Research Has Shown the Benefits of High-Dose Vitmain C?
Have any clinical trials (research studies with people) of high-dose intravenous (IV) vitamin C been conducted?
Several studies of high-dose vitamin C in patients with cancer have been done in recent years, including the following:
Studies of vitamin C alone
- Intravenous (IV) vitamin C was studied in p atients with breast cancer who were treated with adjuvant chemotherapy and radiation therapy. The study found that patients who received IV vitamin C had better quality of life and fewer side effects than those who did not.
- A study of IV vitamin C and high doses of vitamin C taken by mouth was done in patients with cancer that could not be cured. Vitamin C was shown to be a safe and effective therapy to improve quality of life in these patients, including physical, mental, and emotional functions, symptoms of fatigue, nausea and vomiting, pain, and appetite loss.
- Vitamin C has been shown to be safe when given to healthy volunteers and cancer patients at doses up to 1.5 g/kg, while screening out patients with certain risk factors who should avoid vitamin C. Studies have also shown that Vitamin C levels in the blood are higher when taken by IV than when taken by mouth, and last for more than 4 hours.
Studies of vitamin C combined with other drugs
Studies of vitamin C combined with other drugs have shown mixed results:
- In a small study of 14 patients with advanced pancreatic cancer, IV vitamin C was given along with chemotherapy and treatment with a targeted therapy. Patients had very few bad side effects from the vitamin C treatment. The nine patients who completed the treatment had stable disease as shown by imaging studies.
- In another small study of 9 patients with advanced pancreatic cancer, patients were given chemotherapy in treatment cycles of once per week for 3 weeks along with IV vitamin C twice per week for 4 weeks. These patients had disease that did not progress for a period of months. The combined treatment was well tolerated and no serious side effects were reported.
- In a 2014 study of 27 patients with advanced ovarian cancer, treatment with chemotherapy alone was compared to chemotherapy along with IV vitamin C. Patients who received IV vitamin C along with chemotherapy had fewer serious side effects from the chemotherapy.
- Patients with refractory metastatic colorectal cancer or metastatic melanoma treated with IV vitamin C combined with other drugs had serious side effects, the disease got worse, and there was no anticancer effect. These studies were not controlled with a comparison group so it is unclear how much the IV vitamin C contributed to the side effects.
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| Ingredient name | what-it-does | irr. , com. | ID-Rating |
|---|---|---|---|
| Aqua | solvent | ||
| Alumina | viscosity controlling, abrasive/scrub | ||
| Caprylic/Capric Triglyceride | emollient | ||
| Vitis Vinifera Seed Oil | antioxidant, emollient | goodie | |
| Glycerin | skin-identical ingredient, moisturizer/humectant | 0 , 0 | superstar |
| Sodium Polyacrylate | viscosity controlling | ||
| Urea | skin-identical ingredient, moisturizer/humectant | goodie | |
| Myrciaria Dubia Fruit Extract | |||
| Hippophae Rhamnoides Oil | antioxidant, emollient | goodie | |
| Helianthus Annuus Seed Oil | emollient | 0 , 0 | goodie |
| Rosmarinus Officinalis Leaf Extract | antioxidant, soothing, antimicrobial/antibacterial | goodie | |
| Glycine Soja Oil | emollient, perfuming | 0 , 3 | goodie |
| Sodium Hyaluronate | skin-identical ingredient, moisturizer/humectant | 0 , 0 | goodie |
| Panthenol | soothing, moisturizer/humectant | 0 , 0 | goodie |
| Propanediol | solvent, moisturizer/humectant | ||
| Ascorbyl Palmitate | antioxidant | 0 , 2 | icky |
| Tocopherol | antioxidant | 0 - 3 , 0 - 3 | goodie |
| Hydrogenated Vegetable Glycerides Citrate | emollient, emulsifying | ||
| Propylene Glycol | moisturizer/humectant, solvent | 0 , 0 | |
| Lecithin | emollient, emulsifying | goodie | |
| Caprylyl Glycol | moisturizer/humectant, emollient | ||
| Beta-Sitosterol | |||
| Squalene | skin-identical ingredient, antioxidant, emollient | goodie | |
| Phenoxyethanol | preservative | ||
| Lactic Acid | exfoliant, moisturizer/humectant, buffering | superstar | |
| Disodium EDTA | chelating | ||
| Citrus Limon Peel Oil | perfuming | icky | |
| Parfum | perfuming | icky | |
| Limonene | perfuming, solvent | icky | |
| Linalool | perfuming | icky | |
| Hexyl Cinnamal | perfuming | icky | |
| Citral | perfuming | icky | |
| Geraniol | perfuming | icky |
Intravenous High-Dose Vitamin C in Cancer Therapy
Lewis Cantley received his Ph.D. from Cornell University and did his post-doctoral work at Harvard University. He was formerly a professor in the Departments of Systems Biology and Medicine at Harvard Medical School in Boston. He is current the Meyer Director and Professor of Cancer Biology at the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine in New York City. Jihye Yun received her Ph.D. from Johns Hopkins University, School of Medicine under the mentorship of Bert Vogelstein and did her post-doctoral work with Lewis Cantley at Weill Cornell Medicine. She is currently an Assistant Professor and a CPRIT scholar at Baylor College of Medicine in Houston.
The discovery and isolation of vitamin C was one of the most important advances in improving human nutrition. Scurvy, a severe vitamin C deficiency disease characterized by weakness, lethargy, easy bruising and bleeding, was particularly problematic for sailors on long voyages during the 16th century, where access to fresh fruits and vegetables was limited. In fact, scurvy was the leading cause of naval deaths between the 16th and 18th centuries, killing more sailors than all battles, storms and other diseases combined. It wasn’t until 1747 that Scottish naval physician James Lind demonstrated that consuming oranges and lemons cured and prevented scurvy. However, it took scientists nearly two more centuries to identify the nature of the curative substance contained in citrus fruits, now commonly known as vitamin C. The search for this elusive substance ended in 1932 when Albert Szent-Gyorgyi, a Hungarian biochemist, isolated and identified a 6-carbon carbohydrate, hexuronic acid, as the anti-scurvy factor. Shortly thereafter, Szent-Gyorgyi renamed it “a-scorbic acid”, a reference to its anti-scorbutic properties, and later went on to receive the Nobel Prize in Physiology and Medicine in 1937 for his discoveries.
Vita c infusion mikrodermabrazja
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The moisturizing microdermabrasion from the Vita C Infusion line gives your skin a boost. Microdermabrasion cleanses, tones, refreshes and unifies the skin tone. Microdermabrasion dedicated to all skin types. Time [more] [more] of day to use microdermabrasion day and night. The active ingredients of the formula are camu-camu extract and sea buckthorn oil providing a powerful dose of vitamin C and exfoliating micro-crystals. [less]
The controversial history of high-dose vitamin C in cancer treatment
Utilizing high doses of vitamin C as a cancer therapy is no exception to this controversy. Nearly 60 years ago Toronto physician William McCormick observed that cancer patients often presented with severely low levels of vitamin C in their blood and featured scurvy-like symptoms, leading him to postulate that vitamin C might protect against cancer by increasing collagen synthesis. In 1972, extending this theory, Ewan Cameron, a Scottish surgeon, hypothesized that ascorbate could suppress cancer development by inhibiting hyaluronidase, which otherwise weakens the extracellular matrix and enables cancer to metastasize. He began treating terminally ill cancer patients and published a case report of 50 patients in which some of the treated patients benefited from high dose vitamin C.
So why did the Pauling and Mayo Clinic trials have different results? There are at least two crucial differences. First, the Mayo Clinic trials abruptly stopped the ascorbate administration, switching to traditional chemotherapy, when the patient developed signs of tumor progression. Thus, the overall median time of vitamin C treatment under the Mayo Clinic trials was only 2.5 months, while the Pauling and Cameron trials treated patients for the duration of the entire study period or as long as 12 years. Secondly, the Mayo Clinic trials administered 10 g of daily ascorbate to patients only orally, while the Cameron and Pauling trials administered their vitamin C both orally and intravenously. This difference in the two dosage routes proved highly consequential.