U nas zapłacisz kartą
Vita C Infusion Mikrodermabrazja - Twoje Klucze do Promiennej Skóry
Introduction
The outbreak of the novel coronavirus (COVID-19) began in December 2019, and remains a prevalent threat around the world. COVID-19 is highly infectious and has high mortality, especially in patients with underlying health issues (such as diabetes). [1] At present, there is no specific drug for the treatment of COVID-19, and many potential therapeutic drugs have been included in the scope of clinical trials. Several institutions have focused on verifying the therapeutic effect of vitamin C on COVID-19. [2,3]
2.1. Study registration
The present study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols statement guidelines, [9] and has been registered with PROSPERO under the registration number: CRD42021246342.
2.2. Selection criteria
2.2.1. Type of studies
The present study is a randomized controlled trial of high-dose vitamin C infusion in the treatment of COVID-19.
2.2.2. Types of patients
Patients with a mini-mental state examination score > 21,2.2.3. Types of interventions and comparisons
Treatment group: high dose vitamin C intravenous infusion, daily total amount ≥10 g. Control group: the placebo group received bacteriostatic water for injection in the same way, or a small dose of vitamin C, daily total amount ≤2 g.
2.2.4. Types of outcomes
Invasive mechanical ventilation-free days in 28 days,2.3. Exclusion criteria
Articles without full-text access or articles that cannot extract data,Reviews, systematic reviews, abstracts, conferences, dissertations, animal experiments, and other literature.
2.4. Search strategy
The electronic databases searched include PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, China National Knowledge Infrastructure database, Chinese Wanfang database and Chinese Biomedical Literature database. The retrieval time was from the establishment of the database to March 2021. Taking PubMed as an example, the retrieval strategy is shown in Table Table1 1 .
Vita c infusion mikrodermabrazja
Products Ingredients Decode INCI Login Register
Login Register
Follow us on our new Insta page »
The moisturizing microdermabrasion from the Vita C Infusion line gives your skin a boost. Microdermabrasion cleanses, tones, refreshes and unifies the skin tone. Microdermabrasion dedicated to all skin types. Time [more] [more] of day to use microdermabrasion day and night. The active ingredients of the formula are camu-camu extract and sea buckthorn oil providing a powerful dose of vitamin C and exfoliating micro-crystals. [less]
What Drugs Interact with High-Dose Vitamin C?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs. High-dose vitamin C, when combined with some anticancer drugs, may cause them to be less effective. So far, these effects have been seen only in some laboratory and animal studies. No clinical trials have been done to further research these drug interactions in humans.
Laboratory studies and animal studies have been done to find out if high-dose vitamin C may be useful in preventing or treating cancer.
Laboratory studies
Many laboratory studies have been done to find out how high-dose vitamin C may cause the death of cancer cells. The anticancer effect of vitamin C in different types of cancer cells involves a chemical reaction that makes hydrogen peroxide, which may kill cancer cells.
Laboratory studies have shown the following:
- Treatment with high-dose vitamin C slowed the growth and spread of prostate, pancreatic, liver, colon, malignant mesothelioma, neuroblastoma, and other types of cancer cells.
- Combining high-dose vitamin C with certain types of chemotherapy may be more effective than chemotherapy alone:
- Ascorbic acid with arsenic trioxide may be more effective in ovarian cancer cells.
- Ascorbic acid with gemcitabine may be more effective in pancreatic cancer cells.
- Ascorbic acid with gemcitabine and epigallocatechin-3-gallate (EGCG) may be more effective in malignant mesothelioma cells.
However, not all laboratory studies combining vitamin C with anticancer therapies have shown benefit. Combining dehydroascorbic acid, a particular form of vitamin C, with chemotherapy made it less effective in killing some kinds of cancer cells.
Animal studies
Studies of high-dose vitamin C have been done in animal models (animals given a disease either the same as or like a disease in humans).
Concluding Remarks
Vitamin C as a cancer therapy has had a controversial past. What has been intriguing are small clinical trials that suggest some responses, but with no clear rationale for why cancers should respond to vitamin C or a path forward for explaining which patients are most likely to respond. Now a growing number of preclinical studies are showing how high-dose vitamin C might benefit cancer patients. Importantly, these preclinical studies provide a clear rationale and potential biomarkers that may help personalize the therapeutic approach and identify patient populations that are likely to respond to high-dose vitamin C therapy. Since the mechanisms of action of vitamin C are becoming better defined, we can propose vitamin C combinations in a more rational, hypothesis-driven manner. In addition, given the current high financial cost of new cancer drugs, it seems rational to improve the effectiveness of current therapies by studying their clinical interactions with vitamin C. In our view, the implementation of this treatment paradigm could provide benefit to many cancer patients.
This work was supported by the US National Institutes of Health (NIH) grant (R35 CA197588), Stand Up to Cancer–American Association for Cancer Research grant (SU2C-AACR-DT22-17), and the Damon Runyon Cancer Research Foundation. Lewis Cantley is a founder and member of the senior advisory boards of Agios Pharmaceuticals and Petra Pharmaceuticals, which are developing novel therapies for cancer. The Cantley laboratory also receives financial support from Petra Pharmaceuticals.
Taking RAS Research to Space
High-dose vitamin C intravenous infusion in the treatment of patients with COVID-19
c Integrated TCM & Western Medicine Department, Zhuzhou Central Hospital, Zhuzhou, Hunan province, China.
c Integrated TCM & Western Medicine Department, Zhuzhou Central Hospital, Zhuzhou, Hunan province, China.
This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.