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Minoksydyl 5 na brodę - Skuteczność, Bezpieczeństwo i Porady
Czy warto stosować minoksydyl?
Minoxidil jest chętnie stosowanym preparatem, właśnie ze względu na rezultaty oraz wysoki poziom bezpieczeństwa jego włączenia do terapii. Przepadają za nim zarówno Pacjenci, jak i lekarze. Można stosować go w domu, nakładając go miejscowo, jak również w gabinetach kosmetologicznych, po uprzednim zastosowaniu dermarollera. Pomimo tego, że nakładanie preparatu wymaga od Pacjentów dokładności, dyscypliny oraz cierpliwości, zdecydowanie warto wypróbować go, jeżeli borykamy się z nadmiernie wypadającymi włosami. Jedynie w skrajnych przypadkach, w których utrata włosów jest duża i niekontrolowana, pomimo tego, że przynosi efekty, niestety nie spełnia oczekiwań Pacjentów.
Minoxidil jest nieco mniej inwazyjnym lekiem, niż finasteryd, który ma działanie blokujące przeobrażanie się testosteronu, w jego pochodną odpowiedzialną za androgenowe wypadanie włosów. Chociaż jego działanie jest silniejsze, nie znaczy, że powinniśmy rozpoczynać terapię właśnie od niego. Uważa się, że finasteryd przynosi efekty w zakresie ograniczenia wypadania włosów u ponad 80% osób, a jednocześnie powoduje przyrost nowych włosów u ponad 60% Pacjentów. Podobnie jak w przypadku minoksydylu jego skuteczność jest wyższa w okolicach czubka głowy. Stosowanie finasterydu zaleca się wyłącznie mężczyznom. Dowiedz się więcej na temat finasterydu.
Adverse Effects
Although minoxidil is generally well tolerated, topical minoxidil is associated with the following adverse effects, as listed below.[10][20]
Skin irritation: This condition can lead to erythema, discomfort, and a burning sensation on the scalp.
Scaly changes of the scalp: This condition can entail irritation or a potential worsening of seborrheic dermatitis.
Isolated pruritus: appears in the area of application.Oral minoxidil is also associated with significant adverse effects, as listed below.
Rare but severe reactions include pericarditis, pericardial effusion, cardiac tamponade, exacerbating congestive heart failure, and worsening angina.
Oral minoxidil administration can lead to significant hypotension and potential complications such as thrombocytopenia and leukopenia in individuals taking the medication.[22]
Breast tenderness and gynecomastia have also been reported as adverse effects of the medication.[23] Hypertrichosis, edema, tachycardia, and weight gain are also caused by oral minoxidil.Drug-Drug Interactions
Systemic cyclosporine can exacerbate adverse effects such as hypertrichosis when combined with topical minoxidil. Notably, hypertrichosis symptoms significantly improved after discontinuing topical minoxidil for 2 months.[24]
Coadministration of low-dose aspirin and minoxidil may diminish the effectiveness of topical minoxidil. This decrease in effectiveness is attributed to the inhibitory effect of low-dose aspirin on sulfotransferase enzymes in human hair.[25]
Concurrent use of guanethidine with minoxidil can cause severe hypotension.[26]Indications
Topical minoxidil is available in both liquid solution and foam formulations. The liquid form of topical minoxidil contains alcohol and propylene glycol, the 2 crucial molecules that help dissolve the drug in a patient's body, facilitating tissue absorption. Formulations containing 2% and 5% minoxidil commonly treat scalp alopecia in individuals aged 18 and above. Long-term use of minoxidil is necessary to uphold the achieved clinical outcomes of the medication, as these effects diminish when the drug is discontinued.[3][4]
Topical Minoxidil
Off-label uses of topical minoxidil are as follows:
Alopecia areata: Minoxidil has demonstrated the ability to elicit a favorable clinical response when used as a standalone treatment for alopecia areata or in conjunction with other medications, such as corticosteroids.
Chemotherapy-induced alopecia: In this case, minoxidil has exhibited the capacity to reduce hair loss and expedite the process of hair regrowth.
Scarring alopecia: Minoxidil has displayed evidence of having an antifibrotic effect on this condition. Consequently, topical minoxidil treatment could be a viable therapeutic option during the initial stages of dermatoses, leading to scarring alopecia, such as those stemming from scalp burns.
Monilethrix: Minoxidil induces the synchronization of hair follicles entering the anagen phase in patients experiencing this condition.
Hereditary alopecia or hypotrichosis: Minoxidil has demonstrated its beneficial effects by promoting hair shaft thickening in hypotrichosis.
Oral Minoxidil
How Rogaine (Minoxidil) Works for Hair Growth
Rogaine (minoxidil) is an over-the-counter (OTC) medication that treats certain kinds of hair loss. When applied directly to the scalp, Rogaine helps hair grow faster and thicker. Rogaine works by increasing blood flow to the hair follicles, which stimulates hair growth and helps prevent further hair loss.
Different formulations of Rogaine are available. Versions marketed for males include a liquid solution in two strengths (2% and 5%) as well as a 5% foam. Two formulations are marketed for females: a 2% liquid solution and a 5% foam. Despite some slight differences, all Rogaine formulations contain the same active ingredient: minoxidil.
Keep reading to learn more about how Rogaine works, what results to expect, and potential side effects.
