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Progesteron a pryszcze - Prawda czy mit?
Progesteron i hormonska terapija ili terapija zamene hormona
Progesteron se takođe ponekad uzima kao deo terapije zamene hormona kod žena koje su prošle kroz menopauzu, ali koje nisu imale histerektomiju (hirurško uklanjanje materice).
Hormonska terapija obično uključuje uzimanje estrogena za lečenje simptoma menopauze i smanjenje rizika od razvoja određenih bolesti.
Imajte na umu da uzimanje progesterona može izazvati neželjene efekte.
- Glavobolje
- Osetljivost ili bol u grudima
- Povraćanje
- Dijareja
- Zatvor
- Umor
- Promene raspoloženja
- Razdražljivost
- Kijavica
- Kašljanje
- Vaginalni iscedak
Uzimanje progesterona takođe može izazvati ozbiljnije neželjene efekte, kao što su:
- Kvržice u grudima
- Migrene
- Vrtoglavica i nesvestica
- Oštećen govor
- Utrnulost u rukama ili nogama
- Otok ili bol u nogama
- Problemi sa ravnotežom
- Otežano disanje
- Ubrzani rad srca
- Bol u grudima
- Problemi sa vidom
- Nekontrolisano drhtanje u rukama
- Bolovi u stomaku
- Svrab kože ili osip
- Vaginalno krvarenje
- Depresija
Ako osetite bilo koji od ovih ozbiljnih neželjenih efekata, odmah pozovite svog lekara.
Summary
High progesterone is often not something to worry about because your levels rise naturally before your period and during pregnancy. However, sometimes it could be a sign of an underlying condition. If you have high progesterone symptoms and are not pregnant, talk to your healthcare provider. They can help you figure out what may be causing it and whether you need treatment.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
- National Library of Medicine. Progesterone test.
- University of Rochester Medical Center. Progesterone.
- Hormone Health Network. Progesterone and progestins.
- Herrera AY, Faude S, Nielsen SE, Locke M, Mather M. Effects of hormonal contraceptive phase and progestin generation on stress-induced cortisol and progesterone release. Neurobiol Stress. 2019,10:100151. doi:10.1016/j.ynstr.2019.100151
- Wu SP, Li R, DeMayo FJ. Progesterone receptor regulation of uterine adaptation for pregnancy. Trends Endocrinol Metab. 2018,29(7):481-491. doi:10.1016/j.tem.2018.04.001
- National Library of Medicine. Ovarian cysts.
- National Library of Medicine. 21-hydroxylase deficiency.
- National Organization for Rare Disorders. Congenital adrenal hyperplasia.
- Harvard Health. Perimenopause: rocky road to menopause.
- MedlinePlus. Progesterone test.
- American College of Obstetricians and Gynecologists. Evaluating infertility.
By Michelle Pugle
Pulge is a freelance health writer focused on mental health content. She is certified in mental health first aid.
Associated Conditions
Low progesterone levels are associated with certain issues, such as:
- Absent periods (known as amenorrhea)
- Infertility
- Miscarriage
If you have problems getting pregnant, your healthcare provider can check your progesterone levels with a blood test. Recent studies suggest that progesterone supplements may help prevent miscarriages.
Mood and Energy Levels
Estrogen and progesterone interact with chemicals in your brain to control your mood and your general sense of well-being.
One way progesterone does this is via its metabolite, a compound known as allopregnanolone.
This can be beneficial and it may make you feel sleepy or a little low energy right before your period. It also contributes to fatigue that's common during the early part of pregnancy.
For some people, the luteal phase rise in progesterone can cause varying degrees of anxiety and agitation. It is thought that this reaction is caused by a disruption in the processing of allopregnanolone.
Progesterone and progestin: How do they work?
Progesterone is the main pro-gestational steroid hormone secreted by the female reproductive system. It is linked to the menstrual cycle, pregnancy, and development of an embryo. Progestin is an artificial form of progesterone that is used for medical purposes.
The ovaries, placenta, and adrenal glands produce progesterone to regulate the condition of the endometrium, which is the inner lining of the uterus.
Progesterone is a steroid and a hormone. It has some important roles, particularly in the process of reproduction.
The corpus luteum is a temporary endocrine, or hormone-producing, gland that forms from the empty ovarian follicle after ovulation.
If fertilization does not occur, the corpus luteum breaks down, less progesterone is produced, and the levels of progesterone are too low to promote the growth of the uterine wall. As the lining of the womb is no longer maintained by progesterone from the corpus luteum, the lining breaks away, resulting in menstrual bleeding.
If conception occurs, progesterone stimulates the further development of blood vessels in the endometrium, and it stimulates glands in the endometrium to secrete nutrients that nourish the fertilized egg.
Progesterone prepares the tissue lining of the uterus to so that the fertilized egg can be implanted. Progesterone also helps to preserve the endometrium throughout pregnancy.
After conception, the placenta forms. The placenta begins to secrete progesterone to supplement, and surpass, the progesterone already secreted by the corpus luteum.
Levels of progesterone from the placenta remain high during pregnancy. This prevents other eggs from maturing, and it promotes changes in breast tissue to prepare for lactation.
Progesterone levels drop consistently just before the menopause. This is thought to be the major cause of symptoms experienced around the menopause.
